CMP RESOURCES - DRUG DATABASE - ESKALITH

  
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DRUG DATABASE - ESKALITH

Generic Name:
lithium (LITH-ee-um)

Brand Names:
Eskalith®, Eskalith-CR®,Lithobid®, Lithonate®, Lithotabs®

Classification:
Anti-Mania

Issue Date:
1982

Lithium affects the flow of sodium through nerve and muscle cells in the body. Sodium affects excitation or mania. Lithium is used to treat the manic episodes of manic depression. Manic symptoms include hyperactivity, rushed speech, poor judgment, reduced need for sleep, aggression, and anger. Lithium also helps to prevent or lessen the intensity of manic episodes.

  • Before Using This Medicine
  • How To Use This Medicine
  • Precautions While on this Medicine
  • Side Effects
  • Overdosage
  • Drug Interactions

  • Before Using This Medicine

    Do not use this medication without telling your doctor if you are pregnant. It could cause harm to the unborn baby. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment.

    Call your doctor at once if you have any early signs of Eskalith toxicity, such as:

    • nausea
    • vomiting
    • diarrhea
    • drowsiness
    • muscle weakness
    • tremor
    • lack of coordination
    • blurred vision
    • ringing in your ears

    Do not crush, chew, or break an extended-release tablet. Swallow the pill whole.

    Drink extra fluids to keep from getting dehydrated while you are taking Eskalith.

    Tell your doctor if you:

    • have been sweating excessively
    • or if you are sick with fever, vomiting, or diarrhea.

    Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.

    Lithium can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.



    How To Use This Medicine

    Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

    Your doctor may occasionally change your dose to make sure you get the best results from this medication.

    Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.

    Measure the liquid form of Eskalith with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

    Taking Eskalith can make it easier for you to become dehydrated, especially if you have any vomiting or diarrhea, if you are outdoors in the sun, or if you exercise vigorously or sweat more than usual. Dehydration can increase some of the side effects of Eskalith.

    Drink extra fluids each day to keep from getting dehydrated while you are taking Eskalith. Tell your doctor if you have been sweating excessively, or if you are sick with fever, vomiting, or diarrhea for more than a few hours.

    To be sure this medication is not causing harmful effects, your kidney function will need to be tested on a regular basis. Do not miss any scheduled visits to your doctor.

    If you need to have any type of surgery, tell the surgeon ahead of time that you are taking Eskalith.



    Precautions While on this Medicine

    Do not use this medication if you are allergic to Eskalith. Before taking Eskalith, tell your doctor if you are allergic to any drugs, or if you have:

    • heart disease
    • kidney disease
    • underactive thyroid
    • severe or debilitating medical condition
    • dehydrated or have low levels of sodium in your blood (hyponatremia)

    If you have any of these conditions, you may need to receive Eskalith in a hospital, or you may need a dosage adjustment or special tests during treatment.

    This medication can cause harm to an unborn baby. Do not use Eskalith without your doctor's consent if you are pregnant. Tell your doctor if you become pregnant during treatment. Use an effective form of birth control while you are using this medication. Lithium can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

    Older adults may be more sensitive to the effects of this medication.

    Do not give Eskalith to a child younger than 12 years old.



    Overdosage

    Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of a Eskalith overdose include:

    • nausea
    • vomiting
    • diarrhea
    • drowsiness
    • muscle weakness
    • tremor
    • lack of coordination
    • blurred vision
    • ringing in your ears


    Side Effects

    Get emergency medical help if you have any of these signs of an allergic reaction:

    • hives
    • difficulty breathing
    • swelling of your face, lips, tongue, or throat

    Call your doctor at once if you have any of these serious side effects:

    • extreme thirst, urinating more or less than usual
    • weakness
    • fever
    • feeling restless or confused
    • eye pain and vision problems
    • restless muscle movements in your eyes, tongue, jaw, or neck
    • pain
    • cold feeling
    • discoloration in your fingers or toes
    • feeling light-headed
    • fainting
    • slow heart rate
    • hallucinations, seizure (blackout or convulsions)
    • fever with muscle stiffness
    • sweating
    • fast or uneven heartbeats
    • early signs of Eskalith toxicity such as:
      • nausea
      • vomiting
      • diarrhea
      • drowsiness
      • muscle weakness
      • tremor
      • lack of coordination
      • blurred vision
      • or ringing in your ears

    Continue to take Eskalith and talk to your doctor if you have any of these less serious side effects:

    • mild tremor of the hands
    • weakness, lack of coordination
    • mild nausea
    • vomiting
    • loss of appetite
    • stomach pain or upset
    • thinning or drying of the hair
    • itching skin

    Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.



    Drug Interactions

    Before taking Eskalith, tell your doctor if you are taking any other medications, especially any of the following:

    • acetazolamide (Diamox®)
    • aminophylline (Truphylline®)
    • theophylline (Elixophyllin®, Respbid®, Theo-Bid®, Theo-Dur®, Uniphyl®)
    • sodium bicarbonate (Alka-Seltzter®, Bicitra®, Polycitra®, or baking soda home remedy antacid)
    • carbamazepine (Carbatrol®, Tegretol®)
    • fluoxetine (Prozac®)
    • metronidazole (Flagyl®)
    • sodium potassium iodide thyroid medication (Pima®)
    • benazepril (Lotensin®)
    • captopril (Capoten®)
    • fosinopril (Monopril®)
    • enalapril (Vasotec®)
    • lisinopril (Prinivil®, Zestril®)
    • moexipril (Univasc®)
    • perindopril (Aceon®)
    • quinapril (Accupril®)
    • ramipril (Altace®)
    • trandolapril (Mavik®)
    • diltiazem (Tiazac®, Cartia®, Cardizem®)
    • verapamil (Calan®, Covera®, Isoptin®, Verelan®)
    • amiloride (Midamor®, Moduretic®)
    • bumetanide (Bumex®)
    • chlorthalidone (Hygroton®, Thalitone®)
    • ethacrynic acid (Edecrin®)
    • furosemide (Lasix®)
    • hydrochlorothiazide (HCTZ®, HydroDiuril®, Hyzaar®, Lopressor®, Vasoretic®, Zestoretic®)
    • indapamide (Lozol®)
    • metolazone (Mykrox®, Zarxolyn®)
    • spironolactone (Aldactazide®, Aldactone®)
    • triamterene (Dyrenium®, Maxzide®, Dyazide®)
    • torsemide (Demadex®)
    • haloperidol (Haldol®)
    • aripiprazole (Abilify®)
    • chlorpromazine (Thorazine®)
    • clozapine (Clzaril®, Fazaclo®)
    • olanzapine (Zyprexa®)
    • quetiapine (Seroquel®)
    • pimozide (Orap®)
    • risperidone (Risperdal®)
    • ziprasidone (Geodon®)
    • celecoxib (Celebrex®)
    • ibuprofen (Motrin®, Advil®)
    • naproxen (Aleve®, Naprosyn®)
    • diclofenac (Voltaren®)
    • diflunisal (Dolobid®)
    • etodolac (Lodine®)
    • flurbiprofen (Ansaid®)
    • indomethacin (Indocin®)
    • ketoprofen (Orudis®)
    • ketorolac (Toradol®)
    • mefenamic acid (Ponstel®)
    • meloxicam (Mobic®)
    • nabumetone (Relafen®)
    • piroxicam (Feldene®)

    If you are using any of these drugs, you may not be able to use Eskalith or you may need dosage adjustments or special tests during treatment.

    There may be other drugs not listed that can affect Eskalith. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.


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    Last Modified: 09/10/08 10:59 ET